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Journal of Toxicological Sciences

REG1B Modulates IL-6 Secretion to Influence Anti-Colorectal Cancer Immune Responses

REG1B Modulates IL-6 Secretion to Influence Anti-Colorectal Cancer Immune Responses Liuhui Ge¹, Xiuting Ma¹, Tian’ai Yin², Zhilin Sun³, Hui Liu¹, Bohan Dong¹* * Corresponding author: Bohan Dong, Department of Microbiology and Immunology, Wannan Medical College, 22 Wenchang West Road, Wuhu, Anhui241002,P.R.China.E-mail:20100044@wnmc.edu.cn Abstract                   REG1B, as a member of the regenerating protein (REG) family, has diverse biological functions and […]

Mechanism Study of the Active Ingredients in Yizhi Qingxin Formula Regulating Mitochondrial Dysfunction to Improve Alzheimer’s Disease

Xiaochen Guo1a, Lichang Yang2b, Ziqi Ning1c, Yaoyao Zhang1d, Meixia Liu1e*, Yun Wei1f* 1.Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing 100091, China 2.Graduate School, Nanjing University of Chinese Medicine, Nanjing 210023, Jiangsu, China ** These authors contributed equally as corresponding authors. aEmail: gmx80211@163.com e*Email: meixialiu2004@126.com Abstract Background: Mitochondrial dysfunction is a key pathological trigger […]

Ferroptosis in Precancerous Lesions of Gastric Cancer Induced by Serum Containing Isodon amethystoides

Xing Zhang1, Zhe Zhang1 , Chungen Yan1,* 1The Department of Gastroenterology, Shaoxing University Affiliated Hospital, Shaoxing, Zhejiang, 312000, China *Corresponding authors:Chungen Yan; Email addresses: 2010001229@usx.edu.cn (Chungen Yan) Running title:Ferroptosis in Precancerous Lesions Induced by  Isodon amethystoides Abstract: Background: Targeting precancerous lesions of gastric cancer (PLGC), defined as chronic atrophic gastritis accompanied by intestinal metaplasia and atypical hyperplasia, represents a promising strategy […]